Top Suppliers Bleaching Well Water - 3-Amino-4-pyrazole carbosamide hemisulfate – JIN DUN

Short Description:

Product Detail

Product Tags

Feedback (2)

We usually continually offer you the most conscientious consumer services, along with the widest variety of designs and styles with finest materials. These initiatives include the availability of customized designs with speed and dispatch for Ethylene Glycol Methacrylate, Water Recycling Process Steps, Membrane Water Treatment, Therefore, we can meet different inquiries from different clients. Please find our website to check more information from our products.

Top Suppliers Bleaching Well Water - 3-Amino-4-pyrazole carbosamide hemisulfate – JIN DUN Detail:

Intermediate for the synthesis of allopurinol.

It is one of the 3-amino-4-substituted pyrazole series. It can be used as an intermediate to synthesize many pharmacologically effective organic compounds, such as allopurinol, one of the pyrazolopyrimidine derivatives series, the latter since 1963 Since its clinical use, it has been the main drug for the treatment of gout. At present, there are few known methods for synthesizing

3-aminopyrazole-4-carboxamide hemisulfate in China, mainly by reacting malononitrile and triethyl orthoformate to prepare ethoxymethylene malononitrile, and then with The reaction of hydrazine hydrate yields 3-amino-4-cyanopyrazole, which is finally reacted with concentrated sulfuric acid to produce

3-aminopyrazole-4-carboxamide hemisulfate (Chen Huiru, Xiao Guomin et al. 3-aminopyrazole- Synthesis of 4-formamide hemisulfate [J]. Chemical Industry Times, 2008, 6 (22): 39 40), the total yield of synthesis by this method is about 60% (calculated as malononitrile), this method It involves a three-step reaction, the steps are longer, and the reagents used, such as malononitrile and ethoxymethylene malononitrile, are more toxic and expensive. In addition, the 3-aminopyrazole-4 prepared by this method -Formamide hemisulfate has a color that is difficult to remove and requires additional processing, which is more complicated.

There are reports in foreign literature using pyridylamide hydrazone and ethoxymethylene malononitrile as raw materials to obtain 3-amino-4-cyanopyrazole by addition and cyclization, and then react with concentrated sulfuric acid to obtain the target compound (Reuken G Jones. Reactions of orthoesters with activemethylene compounds[J]. J Am Chem Soc. 1952,74(5) :4889 4891). The main raw materials used in this method are expensive, the reaction yield is not high, and the profit of industrial production is low. It must be difficult.

Executive standard: Enterprise Standard
Exterior: Off-white or yellow powder

Package: 25kg/drum
assay（HPLC）content Greater than or equal to 98.0%
purity（HPLC）content Greater than or equal to 99.5%

Product detail pictures:

Related Product Guide:

We pursue the management tenet of "Quality is superior, Service is supreme, Reputation is first", and will sincerely create and share success with all clients for Top Suppliers Bleaching Well Water - 3-Amino-4-pyrazole carbosamide hemisulfate – JIN DUN , The product will supply to all over the world, such as: Sacramento, Zambia, Lisbon, Our company will adhere to "Quality first, , perfection forever, people-oriented , technology innovation"business philosophy. Hard work to keep making progress, innovation in the industry, make every effort to first-class enterprise. We try our best to build the scientific management model, to learn abundant professional knowledge, to develop advanced production equipment and production process , to create the first-call quality products, reasonable price , high quality of service , quick delivery , to give you create new value .

2-Nitrobenzenesulfonyl Chloride