7-ethyl-10-(chlorocarbonyloxy)camptothe cin

Short Description:

CAS no：

Chemical properties: Irinotecan Intermediates

Product Detail

Product Tags

Uses

7-ethyl-10-(chlorocarbonyloxy)camptothe cin is used as the intermediate of Irinotecan.
Irinotecan antitumor drug. It is an inhibitor of DNA synthesis. It is a semi synthetic derivative of camptothecin; Used for preparing irinotecan hydrochloride and irinotecan hydrochloride trihydrate; Large scale clinical trials have shown that irinotecan hydrochloride has obvious inhibitory effects on a variety of tumors, such as colon cancer, small cell lung cancer, rectal cancer and leukemia, and is still effective in fluorouracil resistant cases. Therefore, irinotecan hydrochloride has attracted extensive attention all over the world.

Resource-integrated Product Line

Certificate

JIN DUN Medical has ISO qualification and meets GMP production standards, employed domestic and foreign drug synthesis experts with rich experience to guide company's R&D.

Advantages on Medical Customization

TECHNOL OGY ADVANTAGES
●High Pressure Catalytic Hydrogenation . High Pressure Hydrogenolysis Reaction . Cryogenic Reaction (<-78%C)
●Aromatic Heterocyclic Synthesis
●Rearrangement Reaction
●Chiral Resolution
●Heck, Suzuki,Negishi,Sonogashira . Gignard Reaction

JIN DUN R&D

Equipments

Our Lab has various experimental and testing equipments, such as: NMR (Bruker 400M)、HPLC、chiral-HPLC、LC-MS、LC-MS/MS (API 4000)、IR、UV、GC、GC-MS, Chromatography, Microwave Synthesizer, Parallel Synthesizer, Differential Scanning Calorimeter (DSC), Electron Microscope...

R&D Team

Jindun Medical has a group of professional R&D personnel, and employs many domestic and foreign drug synthesis experts to guide R&D, making our synthesis more accurate and efficient.

Case-Sharing

We have helped several top domestic pharmaceutical companies, such as Hansoh, Hengrui and HEC Pharm. Here we will show part of them.

Customzation Case One:

Cas No.: 110351-94-5

Customzation Case Two:

Cas No.: 144848-24-8

Customzation Case Three:

Cas No.: 200636-54-0

Cooperation Mode

1.Customize New Intermediates or APIs. Same as above case sharing, customers have the demands for specific Intermediates or APIs, and they can not find the needed products in the market, then we can help to Customize.

2.Process Optimization for Old Products. Our team will help to Optimize and improve such production whose reaction route is old, production cost is high, and the efficiency is low. We can provide full documentation for technology transfer and process improvement, help customer for a more efficient production.

From drug targets to INDs, JIN DUN Medical provides you with one-stop personalized R&D solutions.

JIN DUN Medical insists on creating a team with dreams, making dignified products, meticulous, rigorous, and going all out to be a trusted partner and friend of customers!

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